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SWIR Fluorescence Imaging In Vivo Monitoring and Evaluating Implanted M2 Macrophages in Skeletal Muscle Regeneration Article

Mo Chen, Yuzhou Chen, Sijia Feng, Shixian Dong, Luyi Sun, Huizhu Li, Fuchun Chen, Nguyen Thi Kim Thanh, Yunxia Li, Shiyi Chen, You Wang, Jun Chen

《工程(英文)》 doi: 10.1016/j.eng.2023.05.010

摘要:

Skeletal muscle has a robust regeneration ability that is impaired by severe injury, disease, and aging, resulting in a decline in skeletal muscle function. Therefore, improving skeletal muscle regeneration is a key challenge in treating skeletal muscle-related disorders. Owing to their significant role in tissue regeneration, implantation of M2 macrophages (M2Mø) has great potential for improving skeletal muscle regeneration. Here, we present a short-wave infrared (SWIR) fluorescence imaging technique to obtain more in vivo information for an in-depth evaluation of the skeletal muscle regeneration effect after M2Mø transplantation. SWIR fluorescence imaging was employed to track implanted M2Mø in the injured skeletal muscle of mouse models. It is found that the implanted M2Mø accumulated at the injury site for two weeks. Then, SWIR fluorescence imaging of blood vessels showed that M2Mø implantation could improve the relative perfusion ratio on day 5 (1.09 ± 0.09 vs 0.85 ± 0.05; p = 0.01) and day 9 (1.38 ± 0.16 vs 0.95 ± 0.03; p = 0.01) post-injury, as well as augment the degree of skeletal muscle regeneration on day 13 post-injury. Finally, multiple linear regression analyses determined that post-injury time and relative perfusion ratio could be used as predictive indicators to evaluate skeletal muscle regeneration. These results provide more in vivo details about M2Mø in skeletal muscle regeneration and confirm that M2Mø could promote angiogenesis and improve the degree of skeletal muscle repair, which will guide the research and development of M2Mø implantation to improve skeletal muscle regeneration.

关键词: In vivo     Short-wave infrared     Skeletal muscle     Macrophage     Regeneration    

工程材料研究中科学问题的思考

于翘

《中国工程科学》 1999年 第1卷 第3期   页码 1-4

摘要:

在不少场合下,航天用工程材料处在极端条件下工作,这就对材料提出许多特殊的要求,虽然国内外有一定的研究积累,但对更精确的模型和符合特定材料的损伤的状态方程,有待深一步研究。如高级弹头再入时气动加热和粒子云侵蚀以及两者耦合效应引起弹头防护材料增大后退量的问题;空中垃圾和微流星的高速碰撞对航天器的威胁;特别是核爆和激光武器对材料的损伤和破坏,实质上是辐射引起的热击波层裂破坏,这些都属于超高速碰撞对材料的响应问题。天线罩材料、吸波材料、红外隐身材料、电磁屏蔽材料都是具有不同波长电磁波的电磁功能材料,它们对固体介质的穿透、吸收、反射等会产生响应,不同的电磁功能材料,其宏观性能的物理参量不同,但有几个参量是通用的,如介电常数、磁导率和损耗角正切,搞清这些参量与材料微观结构的关系,可以为材料设计和材料创新提供科学依据。

关键词: 天线罩材料     吸波材料     红外隐身材料     电磁兼容材料    

A building unit decomposition model for energy leakage by infrared thermography image analysis

Yan SU, Fangjun HONG, Lianjie SHU

《能源前沿(英文)》 2020年 第14卷 第4期   页码 901-921 doi: 10.1007/s11708-020-0679-y

摘要: A quantitative energy leakage model was developed based on the thermography image data measured for both external and internal building surfaces. The infrared thermography images of both surfaces of doors, windows, and walls of an office building in the Hengqin Campus of University of Macao were taken at various times in a day for four seasons. The transient heat flux for sample units were obtained based on measurements of the seasonal transient local temperature differences and calculations of the effective thermal conductivity from the multiple-layer porous medium conduction model. Effects of construction unit types, orientations, and seasons were quantitatively investigated with unit transient orientation index factors. The corresponding electric energy consumption was calculated based on the air conditioning system coefficient of performance of heat pump and refrigerator cycles for different seasons. The model was validated by comparing to the electric meter records of energy consumption of the air conditioning system. The uncertainties of the predicted total building energy leakage are about 14.7%, 12.8%, 12.4%, and 15.8% for the four seasons, respectively. The differences between the predicted electric consumption and meter values are less than 13.4% and 5.4% for summer and winter, respectively. The typical daily thermal energy leakage value in winter is the highest among the four seasons. However, the daily electric energy consumption by the air conditioning system in summer and autumn is higher than that in winter. The present decomposition model for energy leakage is expected to provide a practical tool for quantitative analysis of energy leakage of buildings.

关键词: heat conductivity     heat coefficient     heat &fllig     ux     infrared thermography     thermal image    

Factors influencing near infrared spectroscopy analysis of agro-products: a review

Xiao XU, Lijuan XIE, Yibin YING

《农业科学与工程前沿(英文)》 2019年 第6卷 第2期   页码 105-115 doi: 10.15302/J-FASE-2019255

摘要:

The near infrared (NIR) spectroscopy technique has wide applications in agriculture with the advantages of being nondestructive, sensitive, safe and rapid. However, there are still more than 40 error sources influencing the robustness and accuracy of its calibration and operation. Environmental, sample and instrument factors that influence the analysis are discussed in this review, including temperature, humidity and other factors that introduce uncertainty. Error sources from livestock products, fruit and vegetables, which are the most common objects in the field of NIR analysis, are also emphasized in the second part. In addition, studies utilizing different instruments, spectral pretreatments, variable selection methods, wavelength ranges, detection modes and calibration methods are tabulated to illustrate the complications they introduce and how they influence NIR analysis. It is suggested that large scale of data with abundant varieties can be used to build a more robust calibration model, in order to improve the robustness and accuracy of the NIR analytical model, and overcome problems caused by confining analysis to too many uniform samples.

关键词: agro-product     error source     influence factor     near infrared spectroscopy    

Spontaneous firing properties of rat medial vestibular nucleus neurons in brain slices by infrared visual

XIA Jiao, KONG Weijia, ZHU Yun, ZHOU Yan, ZHANG Yu, GUO Changkai

《医学前沿(英文)》 2008年 第2卷 第3期   页码 264-268 doi: 10.1007/s11684-008-0050-x

摘要: Domestic application of infrared patch clamp techniques on brain slices is limited. The key of the technique is to prepare high-quality brain slices. The present paper describes the preparation procedure of brainstem slices and the spontaneous firing properties of rat medial vestibular nucleus (MVN) neurons. By infrared differential interference contrast technique, neurons of rat MVN were visualized directly at the depth of 50–100 ?m underneath the surface of slices. Firing activities of MVN neurons were recorded by the whole-cell patch clamp technique in artificial cerebrospinal fluid (ACSF) and low Ca - high Mg fluid. The firing mode was more irregular and depressive in low Ca - high Mg fluid than in ACSF. According to the averaged waveform of action potentials, cells were classified as the neurons with monophasic after-hyperpolarization potential (AHP), and the neurons with biphasic AHP. The resting membrane potential (RMP), input resistance (Rin) and membrane capacitance (Cm) of neurons were recorded and compared between groups. With infrared videomicroscopy, patch clamp recordings could be made under direct observation in freshly prepared brainstem slices. The discharge activities of MVN neurons were spontaneous and the firing mode was modulated by extracellular calcium concentration. The basic membrane properties of two types of neurons were not significantly different, while the differences in waveform might play a role in the segregation between tonic and kinetic cells.

关键词: resistance     infrared     infrared videomicroscopy     depressive     after-hyperpolarization potential    

Modeling of oil near-infrared spectroscopy based on similarity and transfer learning algorithm

Yifei Wang, Kai Wang, Zhao Zhou, Wenli Du

《化学科学与工程前沿(英文)》 2019年 第13卷 第3期   页码 599-607 doi: 10.1007/s11705-019-1807-2

摘要: Near-infrared spectroscopy mainly reflects the frequency-doubled and total-frequency absorption information of hydrogen-containing groups (O‒H, C‒H, N‒H, S‒H) in organic molecules for near-infrared lights with different wavelengths, so it is applicable to testing of most raw materials and products in the field of petrochemicals. However, the modeling process needs to collect a large number of laboratory analysis data. There are many oil sources in China, and oil properties change frequently. Modeling of each raw material is not only unfeasible but also will affect its engineering application efficiency. In order to achieve rapid modeling of near-infrared spectroscopy and based on historical data of different crude oils under different detection conditions, this paper discusses about the feasibility of the application of transfer learning algorithm and makes it possible that transfer learning can assist in rapid modeling using certain historical data under similar distributions under a small quantity of new data. In consideration of the requirement of transfer learning for certain similarity of different datasets, a transfer learning method based on local similarity feature selection is proposed. The simulation verification of spectral data of 13 crude oils measured by three different probe detection methods is performed. The effectiveness and application scope of the transfer modeling method under different similarity conditions are analyzed.

关键词: near-infrared spectroscopy     transfer learning     similarity     modeling    

MEMS-based thermoelectric infrared sensors: A review

Dehui XU, Yuelin WANG, Bin XIONG, Tie LI

《机械工程前沿(英文)》 2017年 第12卷 第4期   页码 557-566 doi: 10.1007/s11465-017-0441-2

摘要:

In the past decade, micro-electromechanical systems (MEMS)-based thermoelectric infrared (IR) sensors have received considerable attention because of the advances in micromachining technology. This paper presents a review of MEMS-based thermoelectric IR sensors. The first part describes the physics of the device and discusses the figures of merit. The second part discusses the sensing materials, thermal isolation microstructures, absorber designs, and packaging methods for these sensors and provides examples. Moreover, the status of sensor implementation technology is examined from a historical perspective by presenting findings from the early years to the most recent findings.

关键词: thermoelectric infrared sensor     CMOS-MEMS     thermopile     micromachining     wafer-level package    

Yuan-zhang Liu: a Short Biography

Anon

《工程管理前沿(英文)》 2014年 第1卷 第1期   页码 113-114 doi: 10.1530/J-FEM-2014016

Near-infrared benzodiazoles as small molecule environmentally-sensitive fluorophores

《化学科学与工程前沿(英文)》 2022年 第16卷 第1期   页码 128-135 doi: 10.1007/s11705-021-2080-8

摘要: The development of fluorophores emitting in the near-infrared spectral window has gained increased attention given their suitable features for biological imaging. In this work, we have optimised a general and straightforward synthetic approach to prepare a small library of near-infrared-emitting C-bridged nitrobenzodiazoles using commercial precursors. C-bridged benzodiazoles have low molecular weight and neutral character as important features that are not common in most near-infrared dyes. We have investigated their fluorescence response in the presence of a wide array of 60 different biomolecules and identified compound 3i as a potential chemosensor to discriminate between Fe2+ and Fe3+ ions in aqueous media.

关键词: fluorescence     probes     iron     screening     library    

Shou-rong Zhang: a Short Biography

Anon.

《工程管理前沿(英文)》 2014年 第1卷 第2期   页码 225-226 doi: 10.15302/J-FEM-2014030

Thermogravimetric coupled with Fourier transform infrared analysis study on thermal treatment of monopotassium

Yuheng FENG, Xuguang JIANG, Yong CHI, Xiaodong LI, Hongmei ZHU

《环境科学与工程前沿(英文)》 2011年 第5卷 第2期   页码 186-192 doi: 10.1007/s11783-011-0322-6

摘要: In China, safe disposal of hazardous waste is more and more a necessity, urged by rapid economic development. The pyrolysis and combustion characteristics of a residue from producing monopotassium phosphate (monopotassium phosphate residue), considered as a hazardous waste, were studied using a thermogravimetric, coupled with Fourier transform infrared analyzer (TG-FTIR). Both pyrolysis and combustion runs can be subdivided into three stages: drying, thermal decomposition, and final devolatilization. The average weight loss rate during fast thermal decomposition stage in pyrolysis is higher than combustion. Acetic acid, methane, pentane, (acetyl) cyclopropane, 2,4,6-trichlorophenol, CO, and CO were distinguished in the pyrolysis process, while CO was the dominant combustion product.

关键词: hazardous waste     combustion     pyrolysis     thermogravimetric coupled with Fourier transform infrared analysis (TG-FTIR)     monopotassium phosphate residue    

Establishing two-stage interaction between fly ash and NaOH by X-ray and infrared analyses

Bhagwanjee JHA,Nevin KOSHY,Devendra Narain SINGH

《环境科学与工程前沿(英文)》 2015年 第9卷 第2期   页码 216-221 doi: 10.1007/s11783-014-0630-8

摘要: The interaction of the fly ash and NaOH, in an open reflux hydrothermal system at 100°C, has been explored by several researchers and formation of fly ash zeolites has been confirmed based on the X-ray diffraction analysis of the residues. However, this method does not reveal much about the characteristic transitions (viz. elemental, electro-negativity and cation exchange capacity) of the residues. In this situation, resorting to Fourier transform-infrared radiation (FT-IR) spectroscopy on the residues obtained from two-stage hydrothermal treatment process, described in this manuscript, appears to be a novel idea to establish transitions in chemical bonds (viz., -Si-OH-Al-, OH-Na, OH-Al-), crystallinity and cation exchange capacity of these residues. Based on extensive studies, it has been demonstrated that FT-IR spectroscopy is extremely useful for 1) detection of chemical bonds in the residues, 2) evaluation of zeolites in the residues and 3) also establishing the superiority of the two-stage interaction of the fly ash with NaOH for synthesizing better fly ash zeolites (viz., Na-P1 and Hydroxysodalte) as compared to those obtained from the conventional single-stage treatment of the fly ash.

关键词: hydrothermal treatment     alkali activation     fly ash zeolites     X-ray diffraction (XRD) and Fourier transform-infrared radiation (FT-IR) spectroscopy    

A hybrid Wavelet-CNN-LSTM deep learning model for short-term urban water demand forecasting

《环境科学与工程前沿(英文)》 2023年 第17卷 第2期 doi: 10.1007/s11783-023-1622-3

摘要:

● A novel deep learning framework for short-term water demand forecasting.

关键词: Short-term water demand forecasting     Long-short term memory neural network     Convolutional Neural Network     Wavelet multi-resolution analysis     Data-driven models    

Study on the crystal morphology and melting behavior of isothermally crystallized composites of short

Mingtao RUN, Hongzan SONG, Yanping HAO

《化学科学与工程前沿(英文)》 2009年 第3卷 第3期   页码 255-264 doi: 10.1007/s11705-009-0008-9

摘要: The spherulites of the short carbon fiber(SCF)/poly (trimethylene terephthalate) (PTT) composites formed in limited space at designed temperatures, and their melting behaviors were studied by the polarized optical microscopy, atomic force microscopy (AFM), and scanning electron microscopy (SEM), respectively. The results suggest that SCF content, isothermal crystallization temperatures, and the film thicknesses influence the crystal morphology of the composites. The dimension of the spherulites is decreased with increasing SCF content, but whether banded or nonbanded spherulites will form in the composites is not dependent on SCF content. However, the crystal morphology of the composites depends strongly on the temperature. When the isothermal crystallization temperatures increase from 180°C to 230°C, the crystal morphology of SCF/PTT composites continuously changes in the following order: nonbanded → banded → nonbanded spherulites. Discontinuous circle lines form in the film when the film thickness increases from 30 to 60 μm. Basing on the SEM observation, it is found that these circle lines are cracks formed due to the constriction difference of the different parts of the spherulites. These cracks are formed when the film is cooled from the isothermal crystallization temperature to the room temperature at a slow cooling rate; while they will disappear gradually at different temperatures in the heating process. The crack will appear/disappear first around the center of the spherulite when the film was cooled/heated. The nontwisted or slightly twisted lamellas will reorganize to form highly twisted lamellas inducing apparent banded texture of the spherulites.

关键词: poly(trimethylene terephthalate)     short carbon fiber     banded spherulites     crack    

Nonlinear finite element analysis of short-limbed wall

Zhi ZHANG, Qian GU, Shaomin PENG, Quanzhi CAI

《结构与土木工程前沿(英文)》 2009年 第3卷 第2期   页码 125-130 doi: 10.1007/s11709-009-0025-2

摘要: Combined with the actual project, this paper carries out a nonlinear finite element analysis on 2 groups, 6 short-limbed shear walls, through the finite element calculation software ANSYS. The stress-strain relation of the models, and the effects of the type of sections and the axial compression ratios on the models can be obtained, providing a reference for future design.

关键词: short-limbed wall (SLW)     nonlinear finite element     separate model     axial compression ratios    

标题 作者 时间 类型 操作

SWIR Fluorescence Imaging In Vivo Monitoring and Evaluating Implanted M2 Macrophages in Skeletal Muscle Regeneration

Mo Chen, Yuzhou Chen, Sijia Feng, Shixian Dong, Luyi Sun, Huizhu Li, Fuchun Chen, Nguyen Thi Kim Thanh, Yunxia Li, Shiyi Chen, You Wang, Jun Chen

期刊论文

工程材料研究中科学问题的思考

于翘

期刊论文

A building unit decomposition model for energy leakage by infrared thermography image analysis

Yan SU, Fangjun HONG, Lianjie SHU

期刊论文

Factors influencing near infrared spectroscopy analysis of agro-products: a review

Xiao XU, Lijuan XIE, Yibin YING

期刊论文

Spontaneous firing properties of rat medial vestibular nucleus neurons in brain slices by infrared visual

XIA Jiao, KONG Weijia, ZHU Yun, ZHOU Yan, ZHANG Yu, GUO Changkai

期刊论文

Modeling of oil near-infrared spectroscopy based on similarity and transfer learning algorithm

Yifei Wang, Kai Wang, Zhao Zhou, Wenli Du

期刊论文

MEMS-based thermoelectric infrared sensors: A review

Dehui XU, Yuelin WANG, Bin XIONG, Tie LI

期刊论文

Yuan-zhang Liu: a Short Biography

Anon

期刊论文

Near-infrared benzodiazoles as small molecule environmentally-sensitive fluorophores

期刊论文

Shou-rong Zhang: a Short Biography

Anon.

期刊论文

Thermogravimetric coupled with Fourier transform infrared analysis study on thermal treatment of monopotassium

Yuheng FENG, Xuguang JIANG, Yong CHI, Xiaodong LI, Hongmei ZHU

期刊论文

Establishing two-stage interaction between fly ash and NaOH by X-ray and infrared analyses

Bhagwanjee JHA,Nevin KOSHY,Devendra Narain SINGH

期刊论文

A hybrid Wavelet-CNN-LSTM deep learning model for short-term urban water demand forecasting

期刊论文

Study on the crystal morphology and melting behavior of isothermally crystallized composites of short

Mingtao RUN, Hongzan SONG, Yanping HAO

期刊论文

Nonlinear finite element analysis of short-limbed wall

Zhi ZHANG, Qian GU, Shaomin PENG, Quanzhi CAI

期刊论文